​Chronic Idiopathic Constipation (CIC)

CIC results from a lack of an adequate number of bowel movements over an extended period of time, usually defined as greater than six months. Patients with chronic constipation often try laxatives and fibre supplements prior to physician prescribed therapy. There are existing treatments for chronic constipation, but these treatments have limitations and frequent unpleasant side effects.  A significant need exists for a better chronic constipation therapy. Worldwide prevalence of the condition is estimated at 11.7%. In the US alone, 36-57 million people are affected (Source: Sperber, 2021).